Reduction in BBB disruption in ipsilateral cortex and striatum by post-ICH treatment with UCN. (A) Representative brain coronal sections (2 mm thickness) show Evans blue extravasation on day 3 post-ICH. (B) Comparisons of dye concentrations in various brain tissues among sham + saline, ICH + saline, and ICH + L-UCN (2.5 μg/kg, i.p.) groups. The dye concentration is expressed as μg/g of tissue weight and calculated from a standard curve obtained from known amounts of the dye. Values are shown as mean ± SD, calculated and analyzed by Student's t test. *p < 0.05, **p < 0.01, vs. ICH + saline group, ##p < 0.01 vs. sham + saline group.