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Table 1 Comparison of physiological parameters in sham + saline, ICH + saline, and ICH + L-UCN (2.5 μg/kg, i.p.) groups.

From: Systemic administration of urocortin after intracerebral hemorrhage reduces neurological deficits and neuroinflammation in rats

    Post-treatment Time (hours)
Parameters Grouping Baseline 0.5 1.0 3.0
HR (beats/min) Sham + Saline (n = 4) 355.7 ± 7.0 378.1 ± 7.9 361.0 ± 29.4 371.3 ± 15.0
  ICH + Saline (n = 6) 349.5 ± 48.3 349.5 ± 41.7 348.8 ± 51.4 335.0 ± 15.9
  ICH + L-UCN (n = 6) 355.9 ± 38.3 356.6 ± 35.1 376.8 ± 31.9* 389.2 ± 53.7*
RT (°C) Sham + Saline (n = 4) 37.2 ± 0.2 37.1 ± 0.3 37.1 ± 0.2 37.0 ± 0.2
  ICH + Saline (n = 6) 36.9 ± 0.2 36.9 ± 0.2 36.9 ± 0.1 35.6 ± 2.4
  ICH + L-UCN (n = 6) 36.9 ± 0.1 37.0 ± 0.1 37.0 ± 0.2 37.0 ± 0.1
pO2 (mmHg) Sham + Saline (n = 4) 92.5 ± 2.5 93.6 ± 7.6 95.2 ± 12.6 102.7 ± 9.5
  ICH + Saline (n = 6) 95.7 ± 10.2 104.0 ± 14.5 104.8 ± 11.7 126.3 ± 29.7
  ICH + L-UCN (n = 6) 100.0 ± 8.8 105.2 ± 12.0 107.3 ± 10.7 107.9 ± 11.2
pCO2 (mmHg) Sham + Saline (n = 4) 50.8 ± 2.9 50.1 ± 3.4 45.3 ± 1.1 44.4 ± 3.7
  ICH + Saline (n = 6) 49.7 ± 3.8 45.0 ± 3.5 46.2 ± 4.6 36.2 ± 12.6
  ICH + L-UCN (n = 6) 46.7 ± 3.6 45.1 ± 2.1 42.6 ± 4.9 43.3 ± 3.2
pH Sham + Saline (n = 4) 7.39 ± 0.02 7.40 ± 0.03 7.41 ± 0.01 7.42 ± 0.03
  ICH + Saline (n = 6) 7.39 ± 0.03 7.40 ± 0.02 7.40 ± 0.01 7.39 ± 0.04
  ICH + L-UCN (n = 6) 7.37 ± 0.04 7.39 ± 0.02 7.42 ± 0.02 7.42 ± 0.02
  1. Values are shown as mean ± SD, calculated and analyzed by Student's t test. *p < 0.05 vs. ICH + saline group. ICH, intracerebral hemorrhage; HR, heart rate; L-UCN, low dose urocortin; i.p., intraperitoneally; RT, rectal temperature.