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Figure 1 | Journal of Neuroinflammation

Figure 1

From: Evaluating the role of IL-11, a novel cytokine in the IL-6 family, in a mouse model of spinal cord injury

Figure 1

IL-11 and IL-11Rα expression is increased after spinal cord injury in wild-type mice. qRT-PCR for temporal gene expression of (A) IL-11 in the spinal cord after SCI demonstrate a peak in gene expression at 24 hours, supported by increasing (B) IL-11 protein levels in the spinal cord as measured via ELISA. qRT-PCR for temporal gene expression of (C) IL-11Rα also revealed an increase in gene expression with time after injury with peak expression occurring later than IL-11. Data represent mean ± SEM (error bars), n = 5 for each uninjured group, n = 5 for time points of qRT-PCR, n = 6 for time points of ELISA. *P <0.05 (one-way ANOVA followed by post hoc Bonferroni test).

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