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Table 10 Frequency of supratentorial and infratentorial brain involvement.

From: Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients

 

Seropositive

(No of patients, %)

Seronegative

(No of patients, %)

p-level

Supratentorial brain lesions at first MRI

   

   Total cohort

63/133 (47.4%)†

16/35 (45.7%)†

n.s.‡

Patients meeting Wingerchuk's 2006

criteria

38/89 (42.7%)

13/26 (50%)

n.s.‡

Supratentorial brain lesions ever

   

   Total cohort

78/133 (58.7%)

21/36 (58.3%)

n.s.‡

Patients meeting Wingerchuk's 2006

criteria

51/89 (57.3%)

16/27 (59.3%)

n.s.‡

Brain stem involvement#

  

n.s.‡

   Total cohort

39/137 (28.5%)

7/38 (18.4%)

n.s.‡

Patients meeting Wingerchuk's 2006

criteria

31/137 (22.6%)

7/38 (18.4%)

n.s.‡

  1. †Considered "compatible with MS" by the reading radiologists in 11 cases (8.9%) in the seropositive group and in 3 cases (9.4%) in the seronegative group (p = n.s.). #Clinical and/or MRI evidence. ‡Fisher's exact test (2-tailed).