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Table 8 Clinical events in the early disease course and long-term outcome.

From: Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients

Early events in the disease course EDSS outcome in patients with long term follow-up (≥ 100 months) (median, range; N) p-level
Motor symptoms at first myelitis* Sensory symptoms at first myelitis* 7 (1.5-10; 29) 5.25 (2-9; 16) p < 0.04§
Motor symptoms at onset Sensory symptoms at onset 8.25 (5.5-10; 8) 4 (2-6.5; 5) p < 0.007§
Tetraparesis at first myelitis* Motor symptoms other than tetraparesis at first myelitis* 8.25 (7-10; 8) 6 (1.5-10; 21) p < 0.003§
> 1 myelitis attacks during the first year 1 myelitis attack during the first year 8 (2.5-10; 7) 5.5 (2-8.5; 11) p < 0.035§
  1. *Irrespective of whether at disease onset or not. EDSS = expanded disability status scale; N = number of patients. § Mann Whitney U test.