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Table 1 Mobility of vesicles in control and IFN-γ-treated WT and GFAP -/- Vim -/- astrocytes under spontaneous conditions and after ATP stimulation

From: IFN-γ-induced increase in the mobility of MHC class II compartments in astrocytes depends on intermediate filaments

Genotype

Stimulation

Control

IFN-γ

TL (μm)

MD (μm)

n

TL (μm)

MD (μm)

n

WT

Spontaneous

1.73 ± 0.02

0.49 ± 0.01

1900

2.36 ± 0.04a

0.83 ± 0.02a

2100

ATP

1.55 ± 0.02b

0.41 ± 0.01b

950

1.70 ± 0.02b

0.47 ± 0.01b

1050

GFAP -/- Vim -/-

Spontaneous

1.51 ± 0.01

0.39 ± 0.01

1700

1.59 ± 0.02a

0.43 ± 0.01a

1600

 

ATP

1.49 ± 0.02

0.37 ± 0.01

850

1.42 ± 0.02b

0.36 ± 0.01b

800

  1. Values are mean ± s.e.m.
  2. n, number of vesicles.
  3. a P < 0.05 vs. controls.
  4. b P < 0.05 vs. spontaneous conditions.