Skip to main content

Table 2 Percentage of directional and non-directional vesicles before and after ATP treatment for control and IFN-γ-treated WT and GFAP -/- Vim -/- astrocytes and slopes of the lines fitted to the vesicle mobility data

From: IFN-γ-induced increase in the mobility of MHC class II compartments in astrocytes depends on intermediate filaments

Genotype Stimulation Control IFN-γ
  Mobility Slope (a ± s.e.m.)a Vesicle Slope (a ± s.e.m.)a Vesicle
    (%)   (%)
WT Spontaneous     
Directional 0.633 ± 0.038c (152)b 8.0 0.575 ± 0.020c (426) 20.3
Non-directional 0.262 ± 0.006 (1748) 92.0 0.219 ± 0.005 (1674) 79.7
ATP     
Directional 0.483 ± 0.056c (49) 5.2 0.597 ± 0.059c (62) 5.9
Non-directional 0.266 ± 0.009 (901) 94.8 0.231 ± 0.007 (988) 94.1
GFAP -/- Vim -/- Spontaneous     
  Directional 0.581 ± 0.068c (75) 4.4 0.553 ± 0.030c (92) 5.7
  Non-directional 0.324 ± 0.008 (1625) 95.6 0.329 ± 0.009 (1508) 94.3
  ATP     
  Directional 0.616 ± 0.069c (33) 3.9 0.781 ± 0.148c (20) 2.5
  Non-directional 0.298 ± 0.010 (817) 96.1 0.279 ± 0.012 (780) 97.5
  1. aThe slope values (a) ± s.e.m were obtained from the linear function fitted to the mobility data in Figure 6.
  2. bValues inside brackets are numbers of vesicles. The slopes of regression lines for mobility data of directional and nondirectional vesicles differed in control and IFN-γ treated WT and GFAP -/- Vim -/- cells under spontaneous conditions and after ATP treatment.
  3. c P <0.001 vs. non-directional mobility.