Figure 2
Effect of LTD 4 on astrocyte migration and TGF-β1-induced migration and proliferation. (A, B), Photomicrographs showing astrocyte migration 24 h after treatment with LTD4 (0.01 to 100 nmol/L) in the absence (A) or presence of TGF-β1 (1 ng/ml, B). Scale bars, 400 μm. (C) Data are reported as mean ± S.E.M.; n = 8; *P <0.05 and **P <0.01 compared with control, # P <0.05 and ## P <0.01 compared with TGF-β1 alone (LTD4 0). (D, E) MFI at 24 h was no significant change 24 h after treatment with LTD4 (0.01 to 100 nM, D) alone or combined with TGF-β1 1 ng/ml (E) (n = 9 for each group, P >0.05).