Figure 1

Constitutive activation of NF-κB in lysMCreIκBα ^fl/fl monocytes. Representative cytospins of naïve CD11b-sorted spleen monocytes from lysMCreIκBα^fl/fl mice (A) or wild-type controls (B) after staining for the NF-κB p65 subunit and nuclear co-staining with TOTO-3. Note the accumulation of active NF-κB in the nucleus of monocytes from a representative lysMCreIκBα^fl/fl mouse (marked by arrows). Bar = 20 μm.