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Table 2 Changes (percent composition) in rat plasma sphingomyelin molecular species following intraventricular infusion with propionic acid (PPA) and phosphate buffered saline (PBS)

From: The enteric bacterial metabolite propionic acid alters brain and plasma phospholipid molecular species: further development of a rodent model of autism spectrum disorders

Molecular weight Molecular species Base/acyl species PBS PPA
703 34:1 18:1/16:0 14.05 ± 1.42 4.63 ± 1.10*
733 36:0 18:0/18:0 2.63 ± 0.47 3.40 ± 1.23
731 36:1 18:1/18:0 1.54 ± 0.32 1.65 ± 0.42
761 38:0 18:0/20:0 12.91 ± 0.37 15.92 ± 0.65*
759 38:1 18:1/20:0 8.36 ± 0.56 5.77 ± 0.24*
789 40:0 18:0/22:0 9.44 ± 2.89 10.39 ± 2.03
811 42:3 18:1/24:2 51.07 ± 0.62 58.24 ± 0.68*
Total%    100 100
∑ Saturates    24.98 ± 1.33 29.72 ± 1.49*
∑ Monounsat    23.95 ± 1.53 12.05 ± 1.57*
∑ Polyunsat    51.06 ± 0.63 58.22 ± 0.68*
  1. Values (nanomole percent by weight composition) represent means ± standard errors. Means in the same row accompanied by asterisks are significantly different between treatments at LSD = 0.05, n = 12 per treatment group. Monounsat, monounsaturated fatty acids; PBS, phosphate buffered saline solution; PPA, propionic acid; polyunsat, polyunsaturated fatty acids. Sphingomyelin molecular species were identified using a precursor ion scan of m/z 184 in ESI positive mode. The lipid components in the table are arranged based on the molecular species composition.