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Table 4 Changes (percent composition) in rat plasma phosphatidylcholine molecular species following intraventricular infusion with propionic acid (PPA) and phosphate buffered saline (PBS)

From: The enteric bacterial metabolite propionic acid alters brain and plasma phospholipid molecular species: further development of a rodent model of autism spectrum disorders

Molecular weight

Molecular species

Plasmalogen or diacyl species

PBS

PPA

706

D30:0

16:0/14:0

0.79 ± 0.42

0.59 ± 0.18

734

D32:0

16:0/16:0

1.39 ± 0.57

2.08 ± 0.14

718

P32:1

p16:0/16:1

0.52 ± 0.39

0.40 ± 0.053

762

D34:0

16:0/18:0

2.90 ± 0.34

3.80 ± 0.32*

760

D34:1

16:0/18:1

9.03 ± 0.73

9.98 ± 1.81

746

P34:1

p16:0/18:1

0.61 ± 0.28

0.52 ± 0.05

758

D34:2

16:0/18:2

20.13 ± 0.23

17.61 ± 0.16*

788

D36:1

18:0/18:1

8.11 ± 0.40

9.87 ± 0.38*

774

P36:1

p18:0/18:1

0.76 ± 0.24

6.24 ± 1.96*

782

D36:4

16:0/20:4

13.23 ± 0.42

11.41 ± 0.22*

814

D38:2

18:1/20:1

4.14 ± 0.24

2.97 ± 0.45*

812

D38:3

18:0/20:3

9.82 ± 2.05

8.70 ± 0.64

810

D38:4

18:0/20:4

23.92 ± 0.41

21.45 ± 0.87*

806

D38:6

16:0/22:6

2.42 ± 0.64

2.60 ± 0.63

834

D40:6

18:0/22:6

2.23 ± 0.68

1.78 ± 0.58

Total%

  

100

100

∑ Saturates

  

3.68 ± 0.58

4.39 ± 1.21

∑ Monounsat

  

18.52 ± 1.57

21.92 ± 2.25

∑ Polyunsat

  

75.89 ± 2.55

66.52 ± 2.09*

∑ Plas

  

1.89 ± 0.86

7.15 ± 1.84*

  1. Values (nanomole percent by weight composition) represent means ± standard errors. Means in the same row accompanied by asterisks are significantly different between treatments at LSD = 0.05, n = 12 per treatment group. D represents diacyl species and P represents plasmalogens species, p denotes a sn-1 vinyl ether (plasmalogen) linkage., Monounsat, monounsaturated fatty acids; PBS, phosphate buffered saline solution; plas, plasmalogens; polyunsat, polyunsaturated fatty acids; PPA, propionic acid. Phosphatidylcholine molecular species were identified using a precursor ion scan of m/z 184 in ESI positive mode. The lipid components in the table are arranged based on the molecular species composition.