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Table 4 Changes (percent composition) in rat plasma phosphatidylcholine molecular species following intraventricular infusion with propionic acid (PPA) and phosphate buffered saline (PBS)

From: The enteric bacterial metabolite propionic acid alters brain and plasma phospholipid molecular species: further development of a rodent model of autism spectrum disorders

Molecular weight Molecular species Plasmalogen or diacyl species PBS PPA
706 D30:0 16:0/14:0 0.79 ± 0.42 0.59 ± 0.18
734 D32:0 16:0/16:0 1.39 ± 0.57 2.08 ± 0.14
718 P32:1 p16:0/16:1 0.52 ± 0.39 0.40 ± 0.053
762 D34:0 16:0/18:0 2.90 ± 0.34 3.80 ± 0.32*
760 D34:1 16:0/18:1 9.03 ± 0.73 9.98 ± 1.81
746 P34:1 p16:0/18:1 0.61 ± 0.28 0.52 ± 0.05
758 D34:2 16:0/18:2 20.13 ± 0.23 17.61 ± 0.16*
788 D36:1 18:0/18:1 8.11 ± 0.40 9.87 ± 0.38*
774 P36:1 p18:0/18:1 0.76 ± 0.24 6.24 ± 1.96*
782 D36:4 16:0/20:4 13.23 ± 0.42 11.41 ± 0.22*
814 D38:2 18:1/20:1 4.14 ± 0.24 2.97 ± 0.45*
812 D38:3 18:0/20:3 9.82 ± 2.05 8.70 ± 0.64
810 D38:4 18:0/20:4 23.92 ± 0.41 21.45 ± 0.87*
806 D38:6 16:0/22:6 2.42 ± 0.64 2.60 ± 0.63
834 D40:6 18:0/22:6 2.23 ± 0.68 1.78 ± 0.58
Total%    100 100
∑ Saturates    3.68 ± 0.58 4.39 ± 1.21
∑ Monounsat    18.52 ± 1.57 21.92 ± 2.25
∑ Polyunsat    75.89 ± 2.55 66.52 ± 2.09*
∑ Plas    1.89 ± 0.86 7.15 ± 1.84*
  1. Values (nanomole percent by weight composition) represent means ± standard errors. Means in the same row accompanied by asterisks are significantly different between treatments at LSD = 0.05, n = 12 per treatment group. D represents diacyl species and P represents plasmalogens species, p denotes a sn-1 vinyl ether (plasmalogen) linkage., Monounsat, monounsaturated fatty acids; PBS, phosphate buffered saline solution; plas, plasmalogens; polyunsat, polyunsaturated fatty acids; PPA, propionic acid. Phosphatidylcholine molecular species were identified using a precursor ion scan of m/z 184 in ESI positive mode. The lipid components in the table are arranged based on the molecular species composition.