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Table 5 Changes (percent composition) in rat brain phosphatidylinositol molecular species following intraventricular infusion with propionic acid (PPA) and phosphate buffered saline (PBS)

From: The enteric bacterial metabolite propionic acid alters brain and plasma phospholipid molecular species: further development of a rodent model of autism spectrum disorders

Molecular weight Molecular species Diacyl species PBS PPA
835 D34:1 16:0/18:1 0.53 ± 0.05 0.54 ± 0.07
859 D36:3 18:1/18:2 1.01 ± 0.14 0.79 ± 0.01*
857 D36:4 16:0/20:4 7.71 ± 0.32 7.02 ± 0.45
887 D38:3 18:0/20:3 9.07 ± 0.69 9.71 ± 0.73
885 D38:4 18:0/20:4 74.17 ± 1.35 74.60 ± 1.27
883 D38:5 18:1/20:4 5.53 ± 0.73 5.44 ± 0.41
881 D38:6 16:0/22:6 0.80 ± 0.04 0.79 ± 0.04
913 D40:4 18:0/22:4 0.41 ± 0.01 0.17 ± 0.03*
909 D40:6 18:0/22:6 0.77 ± 0.10 0.94 ± 0.12
Total%    100 100
∑ Monounsat    0.53 ± 0.05 0.54 ± 0.07
∑ Polyunsat    99.46 ± 0.05 99.46 ± 0.07
  1. Values (nanomole percent by weight composition) represent means ± standard errors. Means in the same row accompanied by asterisks are significantly different between treatments at LSD = 0.05, n = 12 per treatment group. D represents diacyl species. Monounsat, monounsaturated fatty acids; PBS, phosphate buffered saline solution, polyunsat, polyunsaturated fatty acids; PPA, propionic acid. Phosphatidylinositol molecular species were identified using a precursor ion scan of m/z 241 in ESI negative mode. The lipid components in the table are arranged based on the molecular species composition.