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Table 2 Association between single nucleotide polymorphisms (SNPs) and ischemic stroke

From: Association of inflammatory gene polymorphisms with ischemic stroke in a Chinese Han population

Gene rsID Minor allele Risk allele MAF, control:case Additive model FDR
OR 95% CI Pvalue
CCL11 rs4795895 A G 0.05:0.07 1.47 1.13 - 1.92 0.004 0.152
CCL11 rs3744508 A A 0.14:0.12 1.2 1.01 -1.43 0.042 0.547
CCR5 rs1799987 A A 0.46:0.43 1.13 1.00 - 1.27 0.051 0.547
TGFB1 rs1800469 C C 0.48:0.49 0.9 0.80 - 1.11 0.071 0.547
NOS3 rs1799983 T G 0.10:0.11 1.19 0.99 - 1.45 0.072 0.547
CCR2 rs1799864 A A 0.27:0.25 1.11 0.97 - 1.27 0.143 0.614
IL6 rs1800796 G G 0.33:0.31 1.1 0.97 - 1.25 0.144 0.614
IL4R rs1801275 G G 0.17:0.16 1.12 0.96 - 1.32 0.162 0.614
ADRB2 rs1042713 G G 0.44:0.42 1.09 0.96 - 1.23 0.172 0.614
CD14 rs2569190 T T 0.37:0.38 1.09 0.96 - 1.23 0.187 0.614
TNF rs361525 A A 0.05:0.05 1.2 0.90 - 1.61 0.208 0.614
FCERB1 rs569108 G G 0.17:0.16 1.11 0.94 - 1.30 0.217 0.614
LTA rs909253 G G 0.42:0.41 1.08 0.95 - 1.22 0.227 0.614
IL1A rs1800587 T C 0.09:0.10 1.12 0.92 - 1.37 0.258 0.614
LTC4S rs730012 C C 0.15:0.14 1.1 0.93 - 1.30 0.263 0.614
ADRB2 rs1042714 G G 0.07:0.11 1.11 0.92 - 1.34 0.267 0.614
VDR rs2228570 T T 0.45:0.43 1.15 0.89 - 1.49 0.282 0.614
IL10 rs1800872 C A 0.35:0.36 1.07 0.95 - 1.21 0.291 0.614
GC rs7041 G G 0.27:0.26 1.07 0.94 - 1.23 0.321 0.642
VDR rs1544410 A A 0.06:0.05 1.05 0.94 - 1.19 0.387 0.735
IL5RA rs2290608 A A 0.24:0.23 1.06 0.92 - 1.22 0.435 0.787
IL1B rs16944 T T 0.49:0.47 1.05 0.93 - 1.18 0.456 0.788
TNF rs1800629 A A 0.06:0.06 1.09 0.86 - 1.39 0.478 0.79
CTLA4 rs5742909 T C 0.13:0.14 1.06 0.89 - 1.26 0.528 0.81
CSF2 rs25882 T C 0.38:0.39 1.04 0.92 - 1.17 0.533 0.81
TCF7 rs244656 T A 0.12:0.13 1.04 0.87 - 1.25 0.649 0.856
IL4R rs1805015 C C 0.08:0.08 1.05 0.84 - 1.30 0.669 0.856
SELP rs6131 A A 0.19:0.20 1.03 0.89 - 1.20 0.674 0.856
IL13 rs1295686 T C 0.28:0.29 1.03 0.90 - 1.17 0.679 0.856
VCAM1 rs1041163 C T 0.15:0.16 1.03 0.88 - 1.21 0.687 0.856
CXCL12 rs1801157 A G 0.21:0.22 1.03 0.89 - 1.19 0.698 0.856
CTLA4 rs231775 A G 0.31:0.31 1.02 0.90 - 1.16 0.738 0.876
C5 rs17611 G G 0.42:0.42 1.02 0.90 - 1.15 0.768 0.884
IL4R rs1805010 G G 0.48:0.48 1.01 0.90 - 1.14 0.827 0.899
ICAM1 rs5491 T T 0.07:0.06 1.03 0.80 - 1.31 0.828 0.899
UGB rs3741240 A A 0.43:0.43 1.03 0.89 - 1.13 0.965 0.977
NOS2A rs1137933 T T 0.13:0.13 1.00 0.84 - 1.19 0.97 0.977
GC rs4588 A A 0.32:0.32 1.00 0.88 - 1.14 0.977 0.977
  1. OR was calculated using a reference allele that resulted in an OR >1. P value and FDR adjusted for age, sex, body mass index and hypertension status in additive model of inheritance.
  2. FDR = false discovery rate; MAF = minor allele frequency.