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Table 3 Single nucleotide polymorphisms (SNPs) achieving P <0.05 for association with ischemic stroke based on hypertension-stratified population

From: Association of inflammatory gene polymorphisms with ischemic stroke in a Chinese Han population

Gene rsID Minor allele Risk allele MAF, control:case OR 95% CI Pvalue FDR
Non-hypertension         
CCL11 rs4795895 A G 0.07:0.05 1.57 1.05 - 2.66 0.032 0.202
CCL11 rs3744508 A A 0.10:0.16 1.64 1.20 - 2.25 0.002 0.076
LTA rs909253 G G 0.39:0.45 1.29 1.03 - 1.60 0.024 0.182
LTC4S rs730012 C C 0.11:0.16 1.55 1.13 - 2.12 0.007 0.086
TGFB1 rs1800469 C C 0.46:0.46 1.30 1.07 - 1.59 0.009 0.086
FCERB1 rs569108 G G 0.12:0.17 1.49 1.11 - 2.00 0.009 0.086
Hypertension         
CCL11 rs4795895 A G 0.07:0.05 1.45 1.05 - 1.99 0.023 0.291
CCR2 rs1799864 A A 0.23:0.28 1.26 1.06 - 1.49 0.008 0.152
CCR5 rs1799987 A A 0.43:0.48 1.23 1.06 - 1.42 0.007 0.152
  1. Non-hypertension: cases = 397 controls = 347; hypertension: cases = 727 controls = 816. OR was calculated using a reference allele that resulted in an OR >1. P value and FDR adjusted for age, sex and body mass index in additive model of inheritance.
  2. FDR = false discovery rate; MAF = minor allele frequency.