Skip to main content

Table 1 Clinical parameters analysis (quality of life, QoL) according to the Short Form-36 (SF-36) survey and 6 minute walk test (6MWT), comparing the IVIG-treated and placebo group

From: Intravenous immunoglobulin treatment of the post-polio syndrome: sustained effects on quality of life variables and cytokine expression after one year follow up

 

IVIG(n=20)

Placebo(n=21)

Between

SF-36 score

Before

1 year

p

Before

1 year

p

group diff. p

mean (SD)

mean (SD)

mean (SD)

mean (SD)

PF

33.2 (17.9)

39.8 (19.2)

0.014

40.7 (22.7)

41.0 (22.0)

0.761

0.028

RP

30.0 (28.8)

42.5 (39.8)

0.240

50.0 (40.3)

48.0 (40.0)

0.757

0.278

BP

50.8 (18.1)

55.5 (21.6)

0.189

55.4 (24.5)

50.7 (27.3)

0.224

0.075

GH

53.1 (22.4)

61.3 (24.2)

0.058

58.1 (22.5)

61.8 (24.2)

0.190

0.290

VT

43.0 (22.6)

49.3 (27.3)

0.267

46.4 (23.8)

47.3 (22.2)

0.948

0.300

SF

66.9 (24.1)

73.8 (26.6)

0.094

70.8 (26.3)

71.4 (23.8)

0.897

0.191

RE

61.7 (43.6)

66.7 (40.5)

0.665

63.5 (43.3)

73.0 (38.9)

0.261

0.736

MH

74.4 (17.9)

76.0 (19.3)

0.652

72.6 (17.2)

72.5 (17.6)

0.881

0.844

PCS

28.9 (6.1)

32.8 (8.2)

0.021

34.0 (10.0)

33.1 (11.3)

0.394

0.020

MCS

48.7 (13.2)

50.0 (12.5)

0.681

47.6 (12.4)

49.3 (11.9)

0.192

0.531

VAS

31(24)

23(20)

0.013

31(22)

29(28)

0.509

0.449

6MWT, m

351 (110)

400 (112)

<0.001

306 (111)

325 (125)

0.145

0.415

 

n=19

n=19

 

n=20

n=20

  
  1. SF-36 scores range from 0 to 100. 6MWT are recorded in meters.
  2. Physical Functioning (PF), Role-Physical (RP), Bodily Pain (BP), General Health (GH), Vitality (VT), Social Functioning (SF), Role-Emotional (RE) and Mental Health (MH).