Figure 8From: Delayed expression of cell cycle proteins contributes to astroglial scar formation and chronic inflammation after rat spinal cord contusion Cell cycle inhibition by CR8 significantly improves functional recovery after SCI. Both BBB and CBS scores were evaluated 1 day post injury and weekly thereafter in drug- vs. vehicle-treated rats. Both BBB and CBS tests showed a significant beneficial effect of delayed systemic CR8 treatment on functional recovery. The effect of treatment was statistically significant beginning at week 2 as measured by BBB score and beginning at week 3 as measured by CBS score. Both measures showed significantly improved recovery chronically at 4–16 weeks after SCI. *p < 0.05 vs. vehicle group at indicated time point.Back to article page