Figure 6

Microglial/macrophage activation is reduced in neutropenic mice. A) Microphotographs of Mac-2 positive cells (green) 7 days after CCI in the cortex and hippocampus. DAPI was used for nuclear staining (blue). Scalebar is 100 μm. B) Quantification of Mac-2 positive cells in cortex and hippocampus following CCI (black bars, n = 5) or CCI and neutrophil depletion (black bars, n = 5). * indicates significant difference at p < 0.05. Values are mean ± SEM.