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Figure 1 | Journal of Neuroinflammation

Figure 1

From: The CCL2 synthesis inhibitor bindarit targets cells of the neurovascular unit, and suppresses experimental autoimmune encephalomyelitis

Figure 1

Bindarit effects on CCL2 mRNA in cultured microglia. Microglia, prepared from C57BL/6 mouse brain, were incubated with bindarit at the indicated concentrations for 4 hr (A), or exposed to 300 μM bindarit for the indicated times (B). Control cultures received only vehicle. Relative CCL2 RNA levels were determined by qRT-PCR, and effects of bindarit treatment reported as % change compared to control cultures. *P < 0.05; # P < 0.01 (compared to control at 0 concentration or 0 time of bindarit).

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Journal of Neuroinflammation

ISSN: 1742-2094