Figure 6From: The CCL2 synthesis inhibitor bindarit targets cells of the neurovascular unit, and suppresses experimental autoimmune encephalomyelitis CCL2 expression profile during experimental autoimmune encephalomyelitis (EAE). Mice were immunized with MOG peptide to induce EAE. At the indicated days post-immunization, mice were sacrificed and CCL2 mRNA levels determined in the whole brain. CCL2 expression is seen to rapidly rise and fall between days 9 to 21, showing the highest level at day 14.Back to article page