Figure 1
From: CD137 ligand activated microglia induces oligodendrocyte apoptosis via reactive oxygen species
Expression of CD137L on microglia. Expression of CD137L on the murine microglia cell lines N9 and BV-2 and on C57BL/6 primary murine microglia was determined by flow cytometry. Open histogram: Isotype control. Grey histogram: Anti-CD137L monoclonal antibody (clone TKS-1). Primary microglia was also stained for CD11b and CD45. Numbers in panels indicate the percentages of CD137L+ cells.