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Figure 3 | Journal of Neuroinflammation

Figure 3

From: JNK signaling is the shared pathway linking neuroinflammation, blood–brain barrier disruption, and oligodendroglial apoptosis in the white matter injury of the immature brain

Figure 3

JNK activation in microglia, vascular endothelial cells and oligodendrocyte progenitors at 6 h post-insult. Immunofluorescence of the ipsilateral white matter in the lipopolysaccharide (LPS) + hypoxic-ischemic (HI) group showed increased phospho-c-Jun N-terminal kinase (p-JNK) expression in (A) ED1-positive microglia, (B) RECA-positive endothelial cells and (C) O4-positive oligodendrocyte progenitors. Scale bar = 25 μm. Inset scale bar = 5 μm in (A), 10 μm in (B) and 2.5 μm in (C).

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