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Figure 4 | Journal of Neuroinflammation

Figure 4

From: Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study

Figure 4

Gene expression profiles in young, aged, and Alzheimer’s disease (AD) samples using hippocampal tissue show similar patterns of change with qPCR and microarray analysis. qPCR (A,B) demonstrated significant gene upregulation of CD14, TLR2, TL4, TLR7, MYD88 and downregulation of TOLLIP in aging, confirming microarray results (C,D). **** P < 0.0001, ***P < 0.005, **P < 0.01, *P < 0.05.

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Journal of Neuroinflammation

ISSN: 1742-2094