Figure 2
Distribution of high mobility box group 1 (HMGB1) in dorsal root ganglion (DRG) tissue derived from tibial nerve injury (TNI) rats. (A) HMGB1 levels in the cytoplasm of L4/5 DRGs sham and post injury day (PID) 14 TNI DRG ipsilateral to the injury are statistically different (*P < 0.01). (B) HMGB1 levels in nucleus of sham L4/5 and DRG derived from PID14 TNI animals were statistically different (*P < 0.01). (C) Western blot analysis of total HMGB1 protein contents in naïve, sham injured and TNI L4/5 ispilateral to the injury at [PID] 14, P > 0.05.