Representative gels (inset) or changes in uncoupling protein (UCP)-2 relative to cytochrome
oxidase subunit IV (COX-IV), detected in the mitochondrial fraction of samples collected from the CA3 subfield of the hippocampus 24 h after microinjection of 0.5 nmol kainic acid or PBS into the left hippocampal CA3 subfield after pretreatment with 3% dimethyl sulfoxide (DMSO), rosiglitazone (RGZ, 6 nmol) or 500 ng GW9662 applied to
the bilateral CA3 subfield. Values are mean ± standard error of the mean (SEM) of quadruplicate analyses from six animals per experimental group. *P < 0.05 versus sham-control group, +P < 0.05 versus sham-control, DMSO + KA or GW9662 + KA group, and #P < 0.05 versus sham-control, DMSO + KA or RGZ + KA group in the Scheffé multiple-range test.