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Figure 2 | Journal of Neuroinflammation

Figure 2

From: Brain leukocyte infiltration initiated by peripheral inflammation or experimental autoimmune encephalomyelitis occurs through pathways connected to the CSF-filled compartments of the forebrain and midbrain

Figure 2

Immune cell localization in parenchymal and ventricular compartments in the brain of control rat. (A) Leukocytes are preferentially associated with the CPs (illustrated here in the fourth ventricle). A high magnification is shown in the insert. (B) Leukocytes in brain parenchyma are CD68+ cells associated with perivascular spaces. Blood vessels are visualized by laminin. (C) Occasional cells not associated with blood vessels are seen in a subependymal position. Scale bar, 50 μm. 3 V, third ventricle; ep, ependyma; Lm, laminin.

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Journal of Neuroinflammation

ISSN: 1742-2094