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Table 9 Receiver operating characteristic curve analysis of factors predicting 1-year poor functional outcome among 303 patients

From: Relationship between plasma high mobility group box-1 protein levels and clinical outcomes of aneurysmal subarachnoid hemorrhage

 

HMGB1

WFNS score

Modified Fisher score

Criterion

>8.9 ng/mL

>2

>2

Area under curve

0.858

0.909

0.902

95% confidence interval

0.813 to 0.895

0.871 to 0.939

0.863 to 0.933

Sensitivity

84.4

96.7

95.6

95% confidence interval

75.3 to 91.2

90.6 to 99.3

89.0 to 98.7

Specificity

77.0

74.7

69.5

95% confidence interval

70.8 to 82.5

68.3 to 80.3

62.8 to 75.6

+ likelihood ratio

3.67

3.81

3.13

95% confidence interval

3.3 to 4.1

3.5 to 4.2

2.8 to 3.5

- likelihood ratio

0.2

0.045

0.064

95% confidence interval

0.1 to 0.3

0.01 to 0.1

0.02 to 0.2

P value

Reference

0.104

0.163

  1. HMGB1, high mobility group box-1; WFNS, World Federation of Neurological Surgeons.