Figure 6
Accumulation of Aβ proteins following LPS (i.p.) injection and suppression by Pls in the murine PFC. Neurons were stained with NeuN (red). A weak fluorescence for Aβ3–16 immunoreactivity (green) in the Con group (b) increased following LPS treatment (e) and was completely abolished by Pl administration (h). The Aβ3–16 fluorescence merged with the NeuN immunoreactivity, indicating the intracellular localization of Aβ (f). Scale bar: 50 μm. Aβ, β-amyloid; Con, control; i.p., intraperitoneal; LPS, lipopolysaccharide; PFC, prefrontal cortex; Pls, plasmalogens.