Accumulation of Aβ proteins following LPS (i.p.) injection and suppression by Pls in the murine CA1 region of the hippocampus. Neurons were stained with NeuN (red). A weak fluorescence for Aβ3–16 immunoreactivity (green) in the Con group (b) increased following LPS treatment (e) and was markedly attenuated by Pl administration (h). The Aβ3–16 fluorescence merged with the NeuN immunoreactivity, indicating the intracellular localization of Aβ (f and i). Scale bar: 50 μm. Aβ, β-amyloid; Con, control; i.p., intraperitoneal; LPS, lipopolysaccharide; Pls, plasmalogens.