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Figure 2 | Journal of Neuroinflammation

Figure 2

From: Pharmacological inhibition of Akt and downstream pathways modulates the expression of COX-2 and mPGES-1 in activated microglia

Figure 2

Effect of SB216763, a GSK-3 inhibitor, on mPGES-1 and COX-2 immunoreactivity in primary LPS-stimulated rat microglia. A: Immunoblot analysis of protein levels of COX-2, mPGES-1 and β-actin in LPS-activated microglia treated with SB216763 (0.01-10 μM). B: Quantitative densitometric analysis of mPGES-1 and COX-2 protein expression normalized to β-actin loading control. *P < 0.05 with respect to LPS control.

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