Skip to main content
Figure 2. | Journal of Neuroinflammation

Figure 2.

From: Hydrogen sulfide attenuates spatial memory impairment and hippocampal neuroinflammation in beta-amyloid rat model of Alzheimer’s disease

Figure 2.

Effects of NaHS on DNA fragmentation in the hippocampus of rats injected with Aβ 1-40 . (A, B) No TUNEL-reactive cell was detected in the hippocampus from sham and sham + NaHS rats. (C) The significant number of degenerating pyramidal neurons, labeled with the TUNEL technique was observed in the CA1 subfield of the hippocampus. (D) The number of TUNEL-positive neurons significantly decreased in the hippocampus from Aβ1-40-injected rats receiving NaHS. Scale bar: 40 μm. Arrows point to degenerating pyramidal neurons with their nuclei stained with TUNEL technique. (E) Quantitative analysis of % TUNEL-positive neurons. Data are given as mean ± S.E.M.. **P < 0.01 vs. sham; ## P < 0.01 vs.1-40.

Back to article page