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Figure 2 | Journal of Neuroinflammation

Figure 2

From: Characterization and function of the human macrophage dopaminergic system: implications for CNS disease and drug abuse

Figure 2

Human macrophages express dopamine receptors (DRs) 3 and 4 on the plasma membrane. Western blot analysis of isolated plasma membrane (PM) and cytoplasmic (Cyto) proteins from monocyte-derived macrophages (MDM) demonstrated that D3R (2 B, black arrow, ~ 40 kDA) and D4R (2 C, black arrow,~ 48 kDA) were expressed in the PM. Specificity of the membrane protein isolation was confirmed by enrichment of Na+/K+ ATPase and lack of α-tubulin in plasma membrane fractions (B, C).

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Journal of Neuroinflammation

ISSN: 1742-2094