From: Elevated levels of circulating IL-18BP and perturbed regulation of IL-18 in schizophrenia
Characteristics | Healthy control subjects (HC, n = 77) | Schizophrenic patients (SCZ, n = 77) |
---|---|---|
Males/Females (n) | 49/28 | 49/28 |
Age (years ± SEM) | 41.8 ± 1.4 | 40.9 ± 1.3a |
Serum IL-18 (pg/ml ± SEM) | 382 ± 16.5 | 518.2 ± 22.1b |
Serum IL-18BP (ng/ml ± SEM) | 4.9 ± 0.2 | 9.8 ± 0.4b |
Serum free IL-18 (pg/ml ± SEM) | 239.3 ± 9.8 | 253.6 ± 12.1a |
Disease onset age (years ± SEM) | - | 25.4 ± 1.1 |
Duration of illness (years ± SEM) | - | 14.9 ± 1.6 |
Olanzapine equivalents (mg/day ± SEM) | - | 22.3 ± 5.5 |