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Table 1 Clinical and biological characteristics of schizophrenic and healthy control subjects

From: Elevated levels of circulating IL-18BP and perturbed regulation of IL-18 in schizophrenia

 Characteristics 

 Healthy control subjects (HC, n = 77) 

 Schizophrenic patients (SCZ, n = 77) 

Males/Females (n)

49/28

49/28

Age (years ± SEM)

41.8 ± 1.4

40.9 ± 1.3a

Serum IL-18 (pg/ml ± SEM)

382 ± 16.5

518.2 ± 22.1b

Serum IL-18BP (ng/ml ± SEM)

4.9 ± 0.2

9.8 ± 0.4b

Serum free IL-18 (pg/ml ± SEM)

239.3 ± 9.8

253.6 ± 12.1a

Disease onset age (years ± SEM)

-

25.4 ± 1.1

Duration of illness (years ± SEM)

-

14.9 ± 1.6

Olanzapine equivalents (mg/day ± SEM)

-

22.3 ± 5.5

  1. a difference is not significant versus HC; b P <0.0001 versus HC.