Figure 5

CCL4 IR in astrocytes and reactive astrocytes. IFC reveals CCL4 (in green) co-localizing with two types of glial cell markers (red), (A) astrocytic marker GFAP and (B) reactive astrocytic marker Vimentin. CCL4 IR is also present in the astrocytic endfeet of the GFAP positive astrocytes (A). Pictures are taken of representative areas in the CA4 region. The insets are higher power magnifications taken from the same anatomical area, with the added nuclear marker DAPI (blue). Scale bar = 40 μm