Protein expression profiling of inflammatory mediators in human temporal lobe epilepsy reveals co-activation of multiple chemokines and cytokines

Table 4 Summary of all p-values for the post hoc tests

Parameter	HC	HC	HC-CX	HC	HC-CX	CX	CX
	+HS vs – HS	+HS vs Cntrl	+HS vs + HS	-HS vs Cntrl	-HS vs –HS	+HS vs Cntrl	-HS vs Cntrl
IL1 RA	0.64497528	0.116	0.0008	0.137	0.108	0.0005	0.027
IL1a	0.24252404	0.0007	0.687	0.003	0.0722	0.0021	0.171
IL-5	0.706	0.0002	0.0261	0.001	0.705	1.32E-06	0.001
IL-7	0.853	6.65E-05	0.007	3.28E-07	0.469	1.78E-10	7.37E-06
IL-10	4.1619E-06	0.004	2E-06	0.138	0.079	0.068	0.305
IL-13	0.25819279	2.78E-06	0.0449	7.35E-07	0.518	1.16E-06	4.90E-05
IL-22	0.491	4.86E-07	0.0149	9.13E-07	0.478	1.23E-05	0.00023
IL-25	1.8845E-05	0.001	1E-07	0.470	0.0865	3.81E-05	0.001
CCL2	0.376	0.0009	0.0185	0.0006	0.0001	0.372	0.227
CCL3	0.521	0.015	0.106	0.002	0.0132	1.34E-06	0.002
CCL5	0.250	0.006	0.0661	0.001	0.0166	5.78E-07	0.0002
CCL19	0.258	0.045	0.203	0.0015	0.2107	0.002	0.126
CCL22	0.99	0.00029	0.5204	0.0002178	0.1207	2.00E-07	0.001
CXCL9	0.168	0.00020	0.0958	0.001	0.249	1.70E-05	0.003
HGF	0.327	0.001	0.0021	9.61E-08	0.142	0.001	0.006
sICAM1	5.9897E-05	0.004	2E-05	0.052	0.281	0.136	0.147
sVCAM1	0.326	3.01E-05	0.9371	7.48E-05	0.1186	6.88E-09	0.00011
VEGF	0.714	0.001	0.5836	8.71E-05	0.0925	3.09E-10	3.07E-05
IFNa	0.00177	0.002	0.014	0.036	0.1402	0.327	0.318
IL-27	0.0012	0.008	0.0051	0.933	0.4785	3.62E-06	0.022
CCL4	0.795	0.0000108	0.022	0.00001	0.00004	0.49	0.27

All significantly different inflammatory mediators (ANOVA/Kruskal-Wallis) were subjected to post-hoc testing (Students-T test/Mann–Whitney U). Significant p-values are depicted in bold.

ISSN: 1742-2094