Figure 2
From: Neuronal c-Abl activation leads to induction of cell cycle and interferon signaling pathways
Cell cycle activation occurs in the olfactory bulb but not in the CA1 region of the hippocampus in AblPP/tTA mice and decreases with time. Bromodeoxyuridine (BrdU) labeling of wild-type versus AblPP/tTA mice. Cohort A = BrdU labeling at 2 weeks, euthanized at 2 weeks; Cohort B = BrdU labeling at 4 weeks, euthanized at 4 weeks; Cohort C = BrdU labeling at 2 weeks, euthanized at 6 weeks. Scalebars: Dentate, Olfactory bulb = 400 μm, CA1 = 800 μm.