Figure 4
From: Neuronal c-Abl activation leads to induction of cell cycle and interferon signaling pathways
Levels of activated STAT1 are increased in AblPP/tTA mice 2 and 4 weeks off doxycycline. Western blot membranes were probed with antibodies to STAT1 pY701, STAT pS727, STAT1, and β-actin loading control. STAT1 pY701, STAT1 pS727, and STAT1 total protein levels were elevated in AblPP mice expressing constitutively active c-Abl for 2 and 4 weeks compared with wild-type controls.