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Figure 2 | Journal of Neuroinflammation

Figure 2

From: IgG glycan hydrolysis by EndoS inhibits experimental autoimmune encephalomyelitis

Figure 2

Endoglycosidase treatment has a profound effect on IgG glycan hydrolysis in vivo . (A) Total serum IgG levels isolated from EndoS-treated WT mice (n = 6) and PBS-treated treated WT mice (n = 4) at the indicated time after immunization were determined by ELISA. (B) SDS-PAGE Coomassie Blue staining (stain) and lectin blot analysis (LCA) of purified IgG from serum samples drawn from three representative PBS- or EndoS-treated WT mice at indicated times after intravenous injection of 20 μg EndoS or PBS (1 and 8 days).

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