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Figure 2 | Journal of Neuroinflammation

Figure 2

From: Transgenic inhibition of astroglial NF-κB protects from optic nerve damage and retinal ganglion cell loss in experimental optic neuritis

Figure 2

Leukocyte infiltration in the optic nerve of mice with ON. Double immunohistochemistry for the astrocyte-specific marker GFAP (red) and the pan-leukocyte marker CD45 (green) in 10-μm thick cryostat-cut sections of the optic nerve of WT and GFAP-IκBα-dn mice under naïve conditions and at various times after induction of EAE. Nuclei were labeled with DAPI. White arrows: isolated CD45+ leukocytes. Scale bar = 20 μm.

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