The uptake of QDs by microglia depends on clathrin-mediated endocytosis. The internalization of QDs by microglia was blocked dose-dependently by bafilomycin (BAF) (A, B), chlorpromazine (CPZ) (C, D), or cytochalasin B (CTB) (E, F). n = 18-48 cells per condition. ** P < 0.01, *** P < 0.001, vs. Vehicle (0.1% ethanol) or non-treated (NT) by Tukey-Kramer posthoc test. Bars represent mean ± SEM. Scale bar, 20 μm.