Figure 2
From: Prevention of hypoglycemia-induced neuronal death by minocycline
Time course of microglial activation in the hippocampal CA1 region after hypoglycemic brain injury. (A) Representative images of microglial activation on the brain sections at indicated time points after hypoglycemic brain injury. Activated microglia were immunostained with anti-CD11b. Scale bar = 40 μm. (B) Quantification of microglial activation in the hippocampal CA1 area of rats after hypoglycemic brain injury. Microglial activation is scored as described in the Methods and Materials. Data are mean ± standard error of the mean (SEM); # P < 0.05 compared with sham-operated animals, *P < 0.05 compared with injured animals treated with saline (n = 5).