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Table 2 Binding potential values of 11 C-[R]-PK11195 in various brain regions

From: Evaluation of age-related changes in translocator protein (TSPO) in human brain using 11C-[R]-PK11195 PET

   Binding potential (mean ±SD (95% CI))
  Side Adults (n = 15) Children (n = 10) P
Pituitary gland   0.62 ±0.18 (0.49 to 0.75) 0.61 ±0.19 (0.15 to 1.07)* 0.95
Midbrain   0.45 ±0.09 (0.38 to 0.48) 0.41 ±0.08 (0.40 to 0.48) 0.09
Thalamus Left 0.35 ±0.04 (0.33 to 0.37) 0.28 ±0.13 (0.19 to 0.37) 0.08
  Right 0.34 ±0.07 (0.30 to 0.37) 0.29 ±0.12 (0.21 to 0.37) 0.20
Lentiform nucleus Left 0.20 ±0.05 (0.17 to 0.23) 0.19 ±0.07 (0.14 to 0.24) 0.63
  Right 0.15 ±0.05 (0.12 to 0.18) 0.15 ±0.07 (0.09 to 0.21) 0.92
Caudate Left 0.10 ±0.05 (0.07 to 0.13) 0.08 ±0.06 (0.03 to 0.13) 0.45
  Right 0.09 ±0.04 (0.07 to 0.12) 0.08 ±0.05 (0.01 to 0.14) 0.46
Hippocampus Left 0.11 ±0.04 (0.07 to 0.14) 0.07 ±0.04 (0.03 to 0.12) 0.20
  Right 0.10 ±0.06 (0.06 to 0.14) 0.10 ±0.06 (0.04 to 0.15) 0.83
Cerebellum Left 0.10 ±0.04 (0.07 to 0.12) 0.08 ±0.03 (0.05 to 0.11) 0.45
  Right 0.09 ±0.04 (0.07 to 0.11) 0.07 ±0.03 (0.05 to 0.10) 0.24
Frontal cortex Left 0.06 ±0.03 (0.04 to 0.07) 0.05 ±0.01 (0.04 to 0.06) 0.47
  Right 0.05 ±0.03 (0.03 to 0.07) 0.05 ±0.03 (0.03 to 0.07) 0.85
Parietal cortex Left 0.04 ±0.03 (0.02 to 0.05) 0.03 ±0.02 (0.01 to 0.04) 0.64
  Right 0.04 ±0.01 (0.03 to 0.05) 0.04 ±0.03 (0.02 to 0.06) 0.53
Temporal cortex Left 0.05 ±0.03 (0.03 to 0.07) 0.05 ±0.02 (0.03 to 0.07) 0.85
  Right 0.05 ±0.02 (0.03 to 0.06) 0.02 ±0.02 (0.03 to 0.07) 0.91
Occipital cortex Left 0.11 ±0.05 (0.08 to 0.14) 0.11 ±0.04 (0.08 to 0.13) 0.79
  Right 0.12 ±0.03 (0.10 to 0.14) 0.12 ±0.02 (0.10 to 0.13) 0.88
  1. *Pituitary binding potential values available in three children only, as it could not be estimated in seven children because of an inability to reliably delineate the pituitary from the surrounding lymphoid tissue/circular venous plexus in these children. CI confidence intervals; SD standard deviation.