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Figure 1 | Journal of Neuroinflammation

Figure 1

From: Programming of neurotoxic cofactor CXCL-10 in HIV-1-associated dementia: abrogation of CXCL-10-induced neuro-glial toxicity in vitro by PKC activator

Figure 1

Analysis of cytokines and chemokines by Bioplex array on CSF samples (A-C) cytokines and (D, E), chemokines in CSF samples from HIV-D and HIV-ND patients. CSF samples were diluted 1:2 and 50 μl of each sample was used in the Bioplex array. Insets show mean elevated levels of (A) IL-6 (5.5- fold), (B) IFN-γ (2.2- fold), (C) PDGF-β (3.7- fold), (D) CXCL10 (4.6- fold), and (E) MCP-1 (3.4- fold) in CSF from HIV-D patients as compared to levels in HIV-ND patients. CSF, cerebrospinal fluid; HIV-D, HIV-demented; HIV-ND, HIV-nondemented; PGDF, platelet-derived growth factor; MCP, monocyte chemotactic protein.

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Journal of Neuroinflammation

ISSN: 1742-2094