Skip to main content
Figure 8 | Journal of Neuroinflammation

Figure 8

From: Opposing effects of Toll-like receptors 2 and 4 on synaptic stability in the spinal cord after peripheral nerve injury

Figure 8

Representatives images of microglial immunostaining in C57BL/6J wild-type (WT) and Toll-like receptor (TLR)2 knockout (KO) mice (TLR2 −/− ) mice, 1 week after sciatic nerve unilateral axotomy. (A,C) Contralateral side and (B,D) ipsilateral side of WT and TLR2−/− mice. Iba1 expression increased, particularly on the surface of the axotomized neurons of both groups, but no differences between the groups were detected. The dashed circle indicates the motor nucleus containing the alpha motor neurons. (E) Graph representing the ipsilateral:contralateral ratio of the integrated density of pixels (P>0.05). Scale bar: 50 μm.

Back to article page