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Figure 3 | Journal of Neuroinflammation

Figure 3

From: Anti-inflammatory and neuroprotective effects of an orally active apocynin derivative in pre-clinical models of Parkinson’s disease

Figure 3

Diapocynin attenuates inducible nitric oxide synthase (iNOS) expression in the substantia nigra (SN) of MPTP-treated mice. (A) Representative Western blots illustrating the expression of iNOS in SN. (B) Bar graph showing means of Western blot iNOS/β-actin ratios ± SEM in SN of 6 mice per group. (C) Double labeling of glial fibrillary acidic protein (GFAP) and iNOS, and (D) Iba-1 and iNOS in the SN region of ventral midbrain. Images were captured at 30× and 60× magnification. *** P <0.001 vs the control group; * P <0.05 vs the MPTP group.

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