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Table 2 Differences in CSF and serum cytokine levels between high and low cytokine responders at A, B and C

From: Changes in serum and cerebrospinal fluid cytokines in response to non-neurological surgery: an observational study

 

Group

csf IL-2

csf IL-4

csf IL-5

csf IL-8

csf IL-10

csf IL-12

csf IL-13

csf TNF

csf INFγ

serum IL-4

serum IL-8

A

high responders

         

19.30 (10)

22.65 (10)

 

rest of sample

         

16.00 (23)

14.54 (23)

 

U, P -value

n.s.

n.s.

n.s.

 

n.s.

    

92.00, 0.027*

58.50, 0.027*

B

high responders

22.80 (10)

18.10 (10)

19.70 (10)

24.30 (10)

22.70 (10)

23.10 (10)

19.50, 0.001

23.80 (10)

21.50 (10)

 

23.15 (10)

 

rest of sample

13.64 (22)

15.00 (21)

14.24 (21)

12.05 (21)

12.81 (21)

12.62 (21)

11.76 (21)

12.29 (22)

14.23 (22)

 

14.33 (23)

 

U, P -value

47.00, 0.008**

84.00, 0.037*

68.00, 0.042*

22.00, <0.001***

38.00, 0.005**

34.00, <0.001***

16.00, <0.001***

27.00, 0.001***

60.00, 0.016*

n.s.

53.50, 0.016*

C

high responders

24.00 (10)

 

25.00 (10)

25.15 (10)

25.00 (10)

23.35 (10)

25.55 (10)

 

20.65 (10)

  
 

rest of sample

13.09 (22)

 

12.64 (22)

12.57 (22)

12.64 (22)

13.39 (22)

12.39 (22)

 

14.61 (22)

  
 

U, P -value

35.00, 0.002*

n.s.

25.00, <0.001***

23.50, <0.001***

25.00, 0.001***

41.50, 0.001***

 

n.s.

68.50, 0.027

n.s.

n.s.

  1. Differences between groups based on ranks, with mean rank in cytokine levels and number of patients (n) in the different groups for each cytokine is presented, followed by Mann–Whitney U statistics U-values, P-values. The α-level was set to 0.005, *<0.05, ** <0.01, *** ≤0.001.