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Table 2 Differences in CSF and serum cytokine levels between high and low cytokine responders at A, B and C

From: Changes in serum and cerebrospinal fluid cytokines in response to non-neurological surgery: an observational study

  Group csf IL-2 csf IL-4 csf IL-5 csf IL-8 csf IL-10 csf IL-12 csf IL-13 csf TNF csf INFγ serum IL-4 serum IL-8
A high responders           19.30 (10) 22.65 (10)
  rest of sample           16.00 (23) 14.54 (23)
  U, P -value n.s. n.s. n.s.   n.s.      92.00, 0.027* 58.50, 0.027*
B high responders 22.80 (10) 18.10 (10) 19.70 (10) 24.30 (10) 22.70 (10) 23.10 (10) 19.50, 0.001 23.80 (10) 21.50 (10)   23.15 (10)
  rest of sample 13.64 (22) 15.00 (21) 14.24 (21) 12.05 (21) 12.81 (21) 12.62 (21) 11.76 (21) 12.29 (22) 14.23 (22)   14.33 (23)
  U, P -value 47.00, 0.008** 84.00, 0.037* 68.00, 0.042* 22.00, <0.001*** 38.00, 0.005** 34.00, <0.001*** 16.00, <0.001*** 27.00, 0.001*** 60.00, 0.016* n.s. 53.50, 0.016*
C high responders 24.00 (10)   25.00 (10) 25.15 (10) 25.00 (10) 23.35 (10) 25.55 (10)   20.65 (10)   
  rest of sample 13.09 (22)   12.64 (22) 12.57 (22) 12.64 (22) 13.39 (22) 12.39 (22)   14.61 (22)   
  U, P -value 35.00, 0.002* n.s. 25.00, <0.001*** 23.50, <0.001*** 25.00, 0.001*** 41.50, 0.001***   n.s. 68.50, 0.027 n.s. n.s.
  1. Differences between groups based on ranks, with mean rank in cytokine levels and number of patients (n) in the different groups for each cytokine is presented, followed by Mann–Whitney U statistics U-values, P-values. The α-level was set to 0.005, *<0.05, ** <0.01, *** ≤0.001.