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Figure 2 | Journal of Neuroinflammation

Figure 2

From: Acetate supplementation reduces microglia activation and brain interleukin-1β levels in a rat model of Lyme neuroborreliosis

Figure 2

The effect of acetate supplementation on microglia reactivity in rats subjected to neuroborreliosis. Panel (A) shows a representative image of the western blot analysis measuring integrin alpha M chain (CD11b) and immunoreactivity, a surrogate marker of microglia activation, and panel (B) represents the composite measure of the western blot analysis. Panel (C) and (D) show representative images of tomato lectin-positive microglia (Arrows) in infected rats treated with either water or glyceryl triacetate (GTA), respectively. The values in panel B represent the means ± SD expressed in units of fold-increase over naïve rats where ‘a’ represents a significant increase compared to naïve rats and ‘b’ represents a significant difference comparing infected rats treated with GTA to infected rats treated with water (n = 6, P ≤0.05). The reticule in panels C and D represent a length of 10 μm.

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