Figure 3

The effect of acetate supplementation on reactive astrogliosis in rats subjected to neuroborreliosis. Panel (A) shows a representative image of the western blot analysis measuring glial fibrillary acidic protein (GFAP) immunoreactivity, a marker of astroglial activation, and panel (B) is the composite measure of the western blot analysis. Panels (C) and (E) show representative high-magnification images of Cy3-labeled GFAP-positive astroglia in infected rats treated with either water or glyceryl triacetate (GTA), respectively and panels (D) and (F) show low-magnification images of GFAP-positive astrocytes in infected rats treated with either water or GTA, respectively. The values in panel B represent the means ± SD expressed in units of fold-increase over naïve rats with a sample size of seven (naïve), six (infected + water), and five (infected +GTA).