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Figure 4 | Journal of Neuroinflammation

Figure 4

From: Metabotropic glutamate receptor 5 contributes to inflammatory tongue pain via extracellular signal-regulated kinase signaling in the trigeminal spinal subnucleus caudalis and upper cervical spinal cord

Figure 4

Rostro-caudal arrangement of the mean number of pERK-IR cells evoked by noxious mechanical stimulation of the tongue through Vc and C1-C2 both ipsilateral (A, C, and E) and contralateral (B, D, and F) to saline and CFA injection. (A) and (B), day 3; (C) and (D), day 8; (E) and (F), day 15 after saline and CFA injection into the tongue. Rostro-caudal arrangement of the mean number of pERK-IR cells following noxious mechanical stimulation of the tongue in ipsilateral (G) and contralateral (H) Vc and C1-C2 in naive rats. Rostro-caudal arrangement of the mean number of pERK-IR cells in ipsilateral (I) and contralateral (J) Vc and C1-C2 in naive and CFA-injected rats without noxious stimulation. The horizontal bars indicate the range of Vc and C1-C2 across the rostrocaudal dimension. n = 5 in each group. Error bars indicate SEM.

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Journal of Neuroinflammation

ISSN: 1742-2094