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Figure 8 | Journal of Neuroinflammation

Figure 8

From: Metabotropic glutamate receptor 5 contributes to inflammatory tongue pain via extracellular signal-regulated kinase signaling in the trigeminal spinal subnucleus caudalis and upper cervical spinal cord

Figure 8

Effects of i.t. infusion of MPEP or vehicle on MHWT (A) and HHWT (B) values measured on day 8 after CFA injection into the tongue. Successive i.t. MPEP treatment partially but significantly diminished CFA-evoked behavioral hypersensitivity. (C) Effects of i.t. 7 days successive administration of CHPG or saline on MHWT values measured on day 8. n = 5 in each group. Error bars indicate SEM.

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