Figure 8From: Metabotropic glutamate receptor 5 contributes to inflammatory tongue pain via extracellular signal-regulated kinase signaling in the trigeminal spinal subnucleus caudalis and upper cervical spinal cord Effects of i.t. infusion of MPEP or vehicle on MHWT (A) and HHWT (B) values measured on day 8 after CFA injection into the tongue. Successive i.t. MPEP treatment partially but significantly diminished CFA-evoked behavioral hypersensitivity. (C) Effects of i.t. 7 days successive administration of CHPG or saline on MHWT values measured on day 8. n = 5 in each group. Error bars indicate SEM.Back to article page