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Table 3 Associations of PDGFD -858A/C genotype with hypertensive and non-hypertensive ICH

From: A functional variant in promoter region of platelet-derived growth factor-D is probably associated with intracerebral hemorrhage

 

Genotype, n (%)

 

Adjusted ORs

Adjusted

Groups

CC

AC

AA

Models

(95% CI)

P Value

Hypertensive ICH

      

   Controls (n = 445)

239 (53.7)

176 (39.5)

30 (6.8)

 

1.00

 

   Cases (n = 314)

165 (52.5)

126 (40.1)

23 (7.4)

Additive

1.01 (0.78-1.31)

0.96

    

Dominant

0.94 (0.68-1.31)

0.73

    

Recessive

1.15 (0.62-2.15)

0.65

Non-hypertensive ICH

      

   Controls (n = 1083)

629 (58.1)

388 (35.8)

66 (6.1)

 

1.00

 

   Cases (n = 97)

39 (40.2)

50 (51.5)

8 (8.3)

Additive

1.75 (1.24-2.46)

0.001

    

Dominant

2.10 (1.34-3.29)

0.001

    

Recessive

1.77 (0.79-3.95)

0.17

  1. Adjusted OR was obtained on multivariate logistic regression after controlling for age, gender, BMI, smoking, HDL-C, non-HDL-C, TC, TG, fasting plasma glucose, and hypertension. Additive model: CC vs. AC vs.AA; Dominant model: CCvs. AC/AA; Recessive model: CC/AC vs. AA.